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Compelled by the global environmental crisis, the building industry is moving toward a paradigm shift that significantly impacts the way we build, design, and interact with the natural environments around us. The built spaces of the future need to disrupt the conventional design practices that have "elevated" the building sector to the largest contributor of manmade CO2 emissions globally. Achieving net-zero embodied and operational emissions in future construction will require the active participation of design, construction, and building professionals, as well as the prompt implementation of decarbonization solutions. These solutions, which restructure the way humans interact with their ecosystems, entail a reevaluation and reinterpretation of architecture and its role as a transformative agent. GAM 21 collects perspectives and proposals on how to make a radical shift towards environmental transformation successful.